Kidney Cancer

Each year, nearly 75,000 people in the United States are diagnosed with kidney cancer, and approximately 15,000 die from the disease.

Questions and Answers

What are the Warning Signs of Kidney Cancer?

Kidney cancer often does not produce noticeable symptoms in its early stages. As the condition progresses, however, some individuals may begin to experience signs such as:

  • Blood in the urine (hematuria)
  • Persistent pain in the back or side
  • Loss of appetite
  • Unintended weight loss
  • Fatigue
  • Intermittent fever

If you notice any of these symptoms—particularly blood in the urine—it is important to seek medical evaluation promptly. Early detection can significantly improve treatment outcomes and help identify other potential conditions affecting the kidneys or urinary tract.

What are the Risk Factors for Kidney Cancer?

While there is no single known cause of kidney cancer, several factors may increase the risk of developing the disease. Common risk factors include:

  • Aging
  • Smoking
  • Obesity
  • High blood pressure
  • Long-term dialysis
  • A family history of kidney cancer

Certain inherited conditions may also increase risk, including von Hippel–Lindau disease and Birt-Hogg-Dubé syndrome. Understanding these risk factors can help guide early screening and proactive health management.

How is Kidney Cancer Diagnosed?

Your urologist will begin by reviewing your symptoms, medical history, and lifestyle factors, followed by a physical examination. Initial testing may include blood work and a urinalysis to evaluate kidney function and overall urinary tract health.

If kidney cancer is suspected, imaging studies such as CT scans or MRI are typically used to identify any abnormal growths within the kidneys. When imaging reveals a suspicious area, a biopsy may be performed to confirm whether the tissue is cancerous and to help determine the stage of the disease.

Additional imaging or diagnostic tests may be recommended to better assess the size, location, and extent of the tumor. These evaluations help determine whether the cancer is confined to the kidney or has spread to nearby structures or other parts of the body—information that is essential for treatment planning.

Your physician may also assess kidney function through specialized blood tests to ensure the kidneys are working properly, which is especially important when considering treatment options such as surgery.

An accurate diagnosis and staging process allows your care team to develop a personalized and effective treatment plan. Early detection is key to improving outcomes, so it is important to seek evaluation if you experience symptoms such as blood in the urine, persistent back or side pain, or unexplained weight loss. Regular monitoring and follow-up care also play an important role in maintaining long-term kidney health.

How is Kidney Cancer Treated?

If you are diagnosed with kidney cancer, your physician will review treatment options based on the stage, type, and overall extent of the disease. In many cases, surgery is the primary treatment and may involve removing the tumor or, if necessary, the affected kidney. Most individuals can live healthy, active lives with one functioning kidney.

Depending on the specific diagnosis, additional treatments may be recommended. These can include minimally invasive approaches such as cryoablation or radiofrequency ablation to destroy cancer cells, as well as systemic therapies like immunotherapy, targeted therapy, chemotherapy, or radiation therapy to manage more advanced disease.

Following treatment, ongoing follow-up care is essential. Regular appointments and testing help monitor recovery and detect any signs of recurrence early. If you have concerns about kidney cancer or are experiencing symptoms such as blood in the urine, scheduling an evaluation is an important step toward timely diagnosis and care.